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ROXRO PHARMA Announces Positive Clinical Proof Of Concept Results For Novel Intranasal Migraine Treatment

April 29th, 2008 by admin

ROXRO PHARMA, Inc. announced positive top-line data from a clinical study of the company’s novel investigational intranasal pain reliever in the treatment of migraine and related symptoms. The placebo-controlled proof of concept study evaluated the efficacy and safety of ROX-828, an intranasal formulation of the non-steroidal anti-inflammatory (NSAID) pain reliever ketorolac.

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Migraines - The Bane Of My Existence

April 27th, 2008 by admin
First off. I’d like to say that I’m not a member of the medical community. You will not find this article full of medical lingo. I am however, a woman who has suffered from migraines for over 30 years.

Migraines, AAARGH! Everyone who has, or currently having migraines, just upon hearing the word, knows how debilitating they can be. The sensitivity to light, sound, smell, and the vomiting. They can also last for hours. Some people have migraines occasionally, while others, such as myself, have them constantly.

Migraines, according to the medical community, is caused by the sudden constricting and releasing of blood vessels. However, they aren’t 100% sure of this.

Migraines can be brought on by a number of things. Diet, food allergies, hormones, and even a faulty gallbladder. There is still research being done on the relationship between hormones, and migraines. I noticed my migraines had eased up a little when I entered menopause. Unfortunately, for my daughter, she too will suffer from migraines as they are genetic. What a legacy to pass on!

There are many medications to choose from for temporary relief. Over the years I’ve taken; Axert, Zomig, Maxalt, Fioricet, Topamax, Paxil, Cymbalta, Atenolol, and Toprol. There are 3 others, but I don’t recall the names due to the fact, I only took them for 1 day. The only one that seems to work for my migraines is Maxalt. Make you to read or ask about side effects of any medications before taking them. This was something I learned the hard way, after taking a couple of the above listed prescriptions.

There is lots of information out there if you want to go the alternative health route. Herbs such as, Feverfew, and Valerian are worth checking out. Also, caffeine has been known to be of help. Do not drink too much, too often, as this may bring on migraines. I’ve read a couple of articles claiming sex relieves migraines as well. I think whoever wrote those articles, don’t know what a migraine is. If your a migraine sufferer, my heart goes out to you. I hope, one day soon, they’ll find a permanent cure.

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Sensitive Skin A Symptom Of Migraine

April 23rd, 2008 by admin

“Migraine hurts skin” is the headline in the Daily Mirror. The newspaper describes the symptom of sensitive skin, called allodynia, where sufferers of migraine find combing their hair, wearing jewellery or getting dressed “excruciatingly painful”. The newspaper reports that 10% of people in the UK suffer migraine. The Daily Telegraph covers the same story and suggests “two thirds of migraine sufferers reported symptoms of the condition allodynia”.

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Migraine Increases Risk Of Severe Skin Sensitivity And Pain

April 22nd, 2008 by admin

People with migraine are more likely to experience exacerbated skin sensitivity or pain after non-painful daily activities such as rubbing one’s head, combing one’s hair and wearing necklaces or earrings, compared to people with other types of headache, according to a study published in the April 22, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology.

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Concentrating On Different Aspects Of Pain Leads To Breakthrough In Migraine Genetics

April 21st, 2008 by admin

In a new study, published in the American Journal of Human Genetics, researchers were able for the first time to convincingly demonstrate a genomic locus to be linked to migraine susceptibility in two diverse populations. Migraine is the most common cause of episodic headache, and by far the most common neurological cause of a doctor’s visit.

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Treximet (sumatriptan And Naproxen Sodium) Tablets Approved By FDA For Acute Treatment Of Migraine

April 21st, 2008 by admin

GlaxoSmithKline (LSE & NYSE: GSK) and POZEN Inc. (NASDAQ: POZN) announced that the FDA has approved Treximet for the acute treatment of migraine attacks with or without aura in adults. Treximet is the first and only migraine product designed to target multiple mechanisms of migraine by combining a triptan, a class of migraine-specific medicines pioneered by GSK, and an anti-inflammatory pain reliever in a single tablet.

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Teva Announces Tentative Approval Of Generic Maxalt(R) Tablets

April 21st, 2008 by admin

Teva Pharmaceutical Industries Ltd. (Nasdaq: TEVA) announced that the U.S. Food and Drug Administration has granted tentative approval for the Company’s Abbreviated New Drug Application (ANDA) to market its generic version of Merck’s migraine pain treatment Maxalt® (Rizatriptan Benzoate) Tablets, equivalent to 5 mg and 10 mg base. Final approval of this product is anticipated upon expiration of patent protection for the brand product in June 2012.

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Overuse Of Codeine, Oxycodone And Barbiturates Increases Risk Of Chronic Migraine

April 20th, 2008 by admin

People who overuse barbiturates and opioids, such as codeine, butalbital, and oxycodone, to treat migraine are at an increased risk of developing chronic migraine, according to research that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12 - 19, 2008.People with chronic migraine have headaches on 15 or more days a month.

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Migraine Frequency Linked With Women’s Risk Of Cardiovascular Disease

April 20th, 2008 by admin

New research shows women who have weekly migraine are significantly more likely to have a stroke than those with fewer migraines or no migraine at all, but those with lower migraine frequency may face increased risk of heart attacks. The research will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12 - 19, 2008.The Women’s Health Study involved 27,798 women health professionals in the United States who were 45 and older.

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Children With Migraine At Increased Risk Of Sleep Disturbances

April 20th, 2008 by admin

Children with migraine are more likely to have sleep disorders, such as sleep apnea and lack of sleep, than children without migraine, according to research on the effects of headaches on children’s sleep patterns that will be presented at the American Academy of Neurology 60th Anniversary Annual Meeting in Chicago, April 12 - 19, 2008.

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